IE homepage is directed to antispywarebox.com?

Hi, One of my client's computer has this problem, when opening an IE window, it displays "about:blank" in address bar, but in IE window, it displays "Windows Security Center" and a spyware infection alert message, if clicking on the link, IE will be directed to "antispywarebox.com" , how to fix it ?

IE homepage is directed to antispywarebox.com?windows xp sp2

you have spyware

IE homepage is directed to antispywarebox.com?microsoft sql server internet explorer

try this : http://www.AdwareAway.com/antispywarebox...
You probably have a virus and or adware or spyware. If you don't have antivirus software try doing a search for ewido and run a scan from their page. Download avg free antivirus install, update and run. Download spybot, install and run.
try asking jeeves for solutions , http://www.ask.com
Fake virus warnings are usually caused by the Smitfraud hijacker infection. a free tool called SmitFraudFix v2.56 is often a solution. Go here:

http://siri.geekstogo.com/SmitfraudFix.p...
Titan shield %26amp; Antispywarebox.com removal guide here:

http://www.bleepingcomputer.com/forums/t...

Hope this helps!